Immunogen
Synthesized peptide derived from human TBL3 AA range: 486-536
Specificity
This antibody detects endogenous levels of TBL3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 13 WD repeats.,
Fields
>>Ribosome biogenesis in eukaryotes
Human protein sequence Database
Q12788
Mouse protein sequence database
Q8C4J7
Rat protein sequence database
Q5U2W5
Cellular localization
Nucleus, nucleolus .
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