Immunogen
Synthesized peptide derived from human BTG1 AA range: 27-77
Specificity
This antibody detects endogenous levels of BTG1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008],
Function
developmental stage:Its expression is associated with the early G1 phase of the cell cycle.,disease:A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC.,function:Anti-proliferative protein.,similarity:Belongs to the BTG family.,
Human protein sequence Database
P62324
Mouse protein sequence database
P62325
Rat protein sequence database
Q63073
Cellular localization
nucleus,cytoplasm,
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