Immunogen
Synthesized peptide derived from human DSCR3 AA range: 163-213
Specificity
This antibody detects endogenous levels of DSCR3 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the VPS26 family.,tissue specificity:Ubiquitously expressed.,
Gene Name
DSCR3 DCRA DSCRA
Human protein sequence Database
O14972
Mouse protein sequence database
O35075
Rat protein sequence database
Cellular localization
Endosome .
Tissue expression
Ubiquitously expressed.
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