Immunogen
Synthesized peptide derived from human CPSF2 AA range: 456-506
Specificity
This antibody detects endogenous levels of CPSF2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.,similarity:Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.,subunit:Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1.,
Gene Name
CPSF2 CPSF100 KIAA1367
Fields
>>mRNA surveillance pathway
Human protein sequence Database
Q9P2I0
Mouse protein sequence database
O35218
Rat protein sequence database
Cellular localization
Nucleus .
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