Immunogen
Synthesized peptide derived from human UD2A3 AA range: 384-434
Specificity
This antibody detects endogenous levels of UD2A3 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.,function:UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.,similarity:Belongs to the UDP-glycosyltransferase family.,
Gene Name
UGT2A3 UNQ2559/PRO6239
Fields
>>Pentose and glucuronate interconversions;>>Ascorbate and aldarate metabolism;>>Steroid hormone biosynthesis;>>Retinol metabolism;>>Porphyrin metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Biosynthesis of cofactors;>>Bile secretion;>>Chemical carcinogenesis - DNA adducts;>>Chemical carcinogenesis - receptor activation
Human protein sequence Database
Q6UWM9
Mouse protein sequence database
Q8BWQ1
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
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