Immunogen
Synthesized peptide derived from human T2FA AA range: 462-512
Specificity
This antibody detects endogenous levels of T2FA at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
caution:Was reported (PubMed:10428810) to have a protein kinase activity and to autophosphorylates on Ser-385 and Thr-389.,function:TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.,PTM:Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.,similarity:Belongs to the TFIIF alpha subunit family.,subunit:Heterodimer of an alpha and a beta subunit. Interacts with GTF2F2 and CTDP1. Interacts with TAF6/TAFII80.,
Fields
>>Basal transcription factors
Human protein sequence Database
P35269
Mouse protein sequence database
Q3THK3
Rat protein sequence database
Q6AY96
Cellular localization
Nucleus.
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