Immunogen
Synthesized peptide derived from human DLGP2 AA range: 727-777
Specificity
This antibody detects endogenous levels of DLGP2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014],
Function
function:May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.,similarity:Belongs to the SAPAP family.,subcellular location:Postsynaptic density of neuronal cells.,subunit:Interacts with DLG1 and DLG4/PSD-95.,tissue specificity:Expressed in brain and kidney.,
Human protein sequence Database
Q9P1A6
Mouse protein sequence database
Q8BJ42
Rat protein sequence database
P97837
Cellular localization
Cell membrane ; Peripheral membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Postsynaptic density of neuronal cells. .
Tissue expression
Expressed in brain and kidney.
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