Immunogen
Synthesized peptide derived from human NELL2 AA range: 509-559
Specificity
This antibody detects endogenous levels of NELL2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009],
Function
similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 5 VWFC domains.,similarity:Contains 6 EGF-like domains.,subunit:Homotrimer. Binds to PKC beta-1.,
Human protein sequence Database
Q99435
Mouse protein sequence database
Q61220
Rat protein sequence database
Q62918
Cellular localization
Secreted .
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