Immunogen
Synthesized peptide derived from human NIT1 AA range: 32-82
Specificity
This antibody detects endogenous levels of NIT1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the nitrilase protein family with homology to bacterial and plant nitrilases, enzymes that cleave nitriles and organic amides to the corresponding carboxylic acids plus ammonia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
Function
sequence caution:Chimeric cDNA. Its C-terminal exon is derived from the last exon of the DEDD gene.,similarity:Belongs to the UPF0012 family.,similarity:Contains 1 CN hydrolase domain.,tissue specificity:Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.,
Human protein sequence Database
Q86X76
Mouse protein sequence database
Q8VDK1
Rat protein sequence database
Q7TQ94
Cellular localization
[Isoform 2]: Mitochondrion .; [Isoform 1]: Cytoplasm .
Tissue expression
Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
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