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TCEA1 rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-11778

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human TCEA1 AA range: 50-100
Specificity
This antibody detects endogenous levels of TCEA1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
Function
alternative products:Additional isoforms seem to exist,disease:A chromosomal rearrangement involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1.,function:Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.,miscellaneous:S-II binds to RNA-polymerase II in the absence of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TFS-II family.,similarity:Contains 1 TFIIS
Gene Name
TCEA1 GTF2S TFIIS
Protein name
TCEA1
Abbreviation
TCEA1
Other name
Fields
Human gene ID
6917
Human protein sequence Database
P23193
Mouse gene ID
21399
Mouse protein sequence database
P10711
Rat gene ID
362479
Rat protein sequence database
Q4KLL0
Cellular localization
Nucleus.
Tissue expression
Storage
-20°C/1 year

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TCEA1 rabbit pAb

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