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CEL3B rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-11833

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

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Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human CEL3B AA range: 206-256
Specificity
This antibody detects endogenous levels of CEL3B at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009],
Function
Gene Name
CELA3B ELA3B
Protein name
CEL3B
Abbreviation
CEL3B
Other name
Fields
>>Pancreatic secretion;>>Protein digestion and absorption
Human gene ID
23436
Human protein sequence Database
P08861
Mouse gene ID
67868
Mouse protein sequence database
Q9CQ52
Rat gene ID
Rat protein sequence database
Cellular localization
extracellular space,
Tissue expression
Pancreas. Not detectable in keratinocytes.
Storage
-20°C/1 year

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CEL3B rabbit pAb

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