Immunogen
Synthesized peptide derived from human NEUR2 AA range: 69-119
Specificity
This antibody detects endogenous levels of NEUR2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.,function:Hydrolyzes sialylated compounds.,similarity:Belongs to the glycosyl hydrolase 33 family.,similarity:Contains 2 BNR repeats.,tissue specificity:Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2D1.,
Fields
>>Other glycan degradation;>>Sphingolipid metabolism;>>Metabolic pathways
Human protein sequence Database
Q9Y3R4
Mouse protein sequence database
Q9JMH3
Rat protein sequence database
Q64627
Cellular localization
Cytoplasm, cytosol .
Tissue expression
Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1.
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