Immunogen
Synthesized peptide derived from human ELMD2 AA range: 191-241
Specificity
This antibody detects endogenous levels of ELMD2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010],
Function
similarity:Contains 1 ELMO domain.,tissue specificity:Expressed in all tissues tested. In lungs it is expressed in alveolar macrophages and alveolar walls.,
Human protein sequence Database
Q8IZ81
Mouse protein sequence database
Q8BGF6
Rat protein sequence database
Cellular localization
membrane,
Tissue expression
Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls.
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