Immunogen
Synthesized peptide derived from human ISPD AA range: 301-351
Specificity
This antibody detects endogenous levels of ISPD at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein. Mutations in this gene are the cause of Walker-Warburg syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012],
Function
similarity:Belongs to the ispD family.,
Fields
>>Pentose and glucuronate interconversions;>>Mannose type O-glycan biosynthesis;>>Metabolic pathways
Human protein sequence Database
A4D126
Mouse protein sequence database
Q5RJG7
Rat protein sequence database
Q5S6T3
Cellular localization
Cytoplasm, cytosol .
Tissue expression
Ubiquitously expressed, with high expression in brain.