Immunogen
Synthesized peptide derived from human MYL5 AA range: 69-119
Specificity
This antibody detects endogenous levels of MYL5 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008],
Function
miscellaneous:This chain binds calcium.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains.,tissue specificity:Expressed in fetal skeletal muscle and retina.,
Fields
>>Axon guidance;>>Focal adhesion;>>Leukocyte transendothelial migration;>>Regulation of actin cytoskeleton;>>Shigellosis;>>Salmonella infection
Human protein sequence Database
Q02045
Mouse protein sequence database
Rat protein sequence database
Cellular localization
cytosol,muscle myosin complex,
Tissue expression
Expressed in fetal skeletal muscle and retina.
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