Immunogen
Synthesized peptide derived from human SYNM AA range: 166-216
Specificity
This antibody detects endogenous levels of SYNM at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015],
Function
catalytic activity:ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn).,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family.,
Fields
>>Aminoacyl-tRNA biosynthesis
Human protein sequence Database
Q96I59
Mouse protein sequence database
Q8BGV0
Rat protein sequence database
Cellular localization
Mitochondrion matrix . Mitochondrion .