Immunogen
Synthesized peptide derived from human PRD14 AA range: 391-441
Specificity
This antibody detects endogenous levels of PRD14 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011],
Function
function:May be involved in transcriptional regulation.,similarity:Contains 1 SET domain.,similarity:Contains 6 C2H2-type zinc fingers.,
Human protein sequence Database
Q9GZV8
Mouse protein sequence database
E9Q3T6
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level).
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