Immunogen
Synthesized peptide derived from human DB114 AA range: 6-56
Specificity
This antibody detects endogenous levels of DB114 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1：50-200. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli, S. aureus, and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS), a factor involved in inflammatory diseases and male reproductive issues. [provided by RefSeq, Nov 2014],
Function
function:Has antibacterial activity.,similarity:Belongs to the beta-defensin family.,
Human protein sequence Database
Q30KQ6
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Expressed in epididymis, predominantly in the caput (at protein level).
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