Immunogen
Synthesized peptide derived from human CSAD AA range: 195-245
Specificity
This antibody detects endogenous levels of CSAD at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
Function
catalytic activity:3-sulfino-L-alanine = hypotaurine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 2/2.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,
Fields
>>beta-Alanine metabolism;>>Taurine and hypotaurine metabolism;>>Pantothenate and CoA biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q9Y600
Mouse protein sequence database
Q9DBE0
Rat protein sequence database
Q64611
Tissue expression
Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.
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