Immunogen
Synthesized peptide derived from human SYFM AA range: 294-344
Specificity
This antibody detects endogenous levels of SYFM at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Function
catalytic activity:ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family.,similarity:Contains 1 FDX-ACB domain.,subunit:Monomer.,
Gene Name
FARS2 FARS1 HSPC320
Fields
>>Aminoacyl-tRNA biosynthesis
Human protein sequence Database
O95363
Mouse protein sequence database
Q99M01
Rat protein sequence database
Q6AYQ3
Cellular localization
Mitochondrion matrix . Mitochondrion .
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