Immunogen
Synthesized peptide derived from human FAN1 AA range: 801-851
Specificity
This antibody detects endogenous levels of FAN1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016],
Function
similarity:Belongs to the MTMR15 family.,
Gene Name
FAN1 KIAA1018 MTMR15
Fields
>>Fanconi anemia pathway
Human protein sequence Database
Q9Y2M0
Mouse protein sequence database
Q69ZT1
Rat protein sequence database
Cellular localization
Nucleus . Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496). .
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车