Immunogen
Synthesized peptide derived from human Fabp1
Specificity
This antibody detects endogenous levels of Human Fabp1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011],
Function
domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
Other name
Fatty acid-binding protein, liver (Fatty acid-binding protein 1;Liver-type fatty acid-binding protein;L-FABP)
Fields
>>PPAR signaling pathway;>>Alcoholic liver disease;>>Fat digestion and absorption
Human protein sequence Database
P07148
Mouse protein sequence database
P12710
Rat protein sequence database
P02692
Cellular localization
Cytoplasm.
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