Molecular weight (DA)
102kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPRIN1. AA range:231-280
Specificity
GRIN1 Polyclonal Antibody detects endogenous levels of GRIN1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in neurite outgrowth.,PTM:Palmitoylation on Cys-999 and/or Cys-1000 is required for membrane targeting.,subcellular location:Highly enriched in growth cone.,subunit:Interacts with activated forms of GNAI1, GNAO1 and GNAZ.,tissue specificity:Widely expressed in the central nervous system, with highest levels in spinal cord.,
Function
function:May be involved in neurite outgrowth.,PTM:Palmitoylation on Cys-999 and/or Cys-1000 is required for membrane targeting.,subcellular location:Highly enriched in growth cone.,subunit:Interacts with activated forms of GNAI1, GNAO1 and GNAZ.,tissue specificity:Widely expressed in the central nervous system, with highest levels in spinal cord.,
Protein name
G protein-regulated inducer of neurite outgrowth 1
Other name
GPRIN1; KIAA1893; G protein-regulated inducer of neurite outgrowth 1; GRIN1
Human protein sequence Database
Q7Z2K8
Mouse protein sequence database
Q3UNH4
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor . Cell projection, growth cone . Highly enriched in growth cone. .
Tissue expression
Widely expressed in the central nervous system, with highest levels in spinal cord.
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