Molecular weight (DA)
31kD
Immunogen
Synthesized peptide derived from M6A . at AA range: 140-220
Specificity
M6A Polyclonal Antibody detects endogenous levels of M6A protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the myelin proteolipid protein family.,
Function
similarity:Belongs to the myelin proteolipid protein family.,
Protein name
Neuronal membrane glycoprotein M6-a
Other name
GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
Human protein sequence Database
P51674
Mouse protein sequence database
P35802
Rat protein sequence database
Q812E9
Cellular localization
Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Cell projection, growth cone . Cell projection, dendritic spine . Cell projection, filopodium . Cell projection, neuron projection . Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons (By similarity). Localized to the growth cone edge membrane of elongating axons (By similarity). .
Tissue expression
Brain,Brain cortex,Fetal brain,Spinal cord,
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