Molecular weight (DA)
36-50kD
Immunogen
Synthetic Peptide of Mas1
Specificity
The antibody detects endogenous Mas1 protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Dilution rate
WB: 1:2000-5000 IHC: 1:200-500. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012],
Function
caution:Was originally (PubMed:3419518) thought to be a receptor for angiotensin II.,disease:The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
Proto-oncogene Mas
Other name
MAS1; MAS; Proto-oncogene Mas
Fields
>>Neuroactive ligand-receptor interaction;>>Renin-angiotensin system;>>Coronavirus disease - COVID-19
Human protein sequence Database
P04201
Mouse protein sequence database
P30554
Rat protein sequence database
P12526
Cellular localization
Cell membrane ; Multi-pass membrane protein .
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