Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GALR3. AA range:291-340
Specificity
GALR3 Polyclonal Antibody detects endogenous levels of GALR3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008],
Function
function:Receptor for the hormone galanin.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
Galanin receptor type 3
Other name
GALR3; GALNR3; Galanin receptor type 3; GAL3-R; GALR-3
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
O60755
Mouse protein sequence database
O88853
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Uterus,
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