Molecular weight (DA)
59kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR114. AA range:91-140
Specificity
GPR114 Polyclonal Antibody detects endogenous levels of GPR114 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the adhesion family of G-protein coupled receptors. Members of this family are characterized by long N-termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,
Protein name
Probable G-protein coupled receptor 114
Other name
GPR114; PGR27; Probable G-protein coupled receptor 114; G-protein coupled receptor PGR27
Human protein sequence Database
Q8IZF4
Mouse protein sequence database
Q3V3Z3
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed in immune cells. Primarily found in granulocytes. Found in eosinophils.
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