Molecular weight (DA)
89kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR156. AA range:501-550
Specificity
GPR156 Polyclonal Antibody detects endogenous levels of GPR156 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
G protein-coupled receptors (GPCRs) are a large superfamily of cell surface receptors characterized by 7 helical transmembrane domains, together with N-terminal extracellular and C-terminal intracellular domains.[supplied by OMIM, Mar 2008],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.,tissue specificity:Ubiquitous expression both in the CNS and in peripheral tissues. Very high expression in fetal brain and testis relative to expression in other tissues.,
Protein name
Probable G-protein coupled receptor 156
Other name
GPR156; GABABL; PGR28; Probable G-protein coupled receptor 156; G-protein coupled receptor PGR28; GABAB-related G-protein coupled receptor
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
Q8NFN8
Mouse protein sequence database
Q6PCP7
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Ubiquitous expression both in the CNS and in peripheral tissues. Very high expression in fetal brain and testis relative to expression in other tissues.
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