Molecular weight (DA)
47kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR173. AA range:251-300
Specificity
GPR173 Polyclonal Antibody detects endogenous levels of GPR173 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at high levels in brain and ovary. Lower levels in small intestine. In brain regions, detected in all regions tested. Highest levels in the cerebellum and cerebral cortex.,
Protein name
Probable G-protein coupled receptor 173
Other name
GPR173; SREB3; Probable G-protein coupled receptor 173; Super conserved receptor expressed in brain 3
Human protein sequence Database
Q9NS66
Mouse protein sequence database
Q6PI62
Rat protein sequence database
Q9JJH2
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed in the ovary, specifically in granulosa cells of follicles that have passed the primary stage and in oocytes (at protein level) (PubMed:30933929). Expressed at high levels in brain. Lower levels in small intestine. In brain regions, detected in all regions tested. Highest levels in the cerebellum and cerebral cortex.
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