Molecular weight (DA)
41kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR175. AA range:198-247
Specificity
GPR175 Polyclonal Antibody detects endogenous levels of GPR175 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
TPRA1 is a gene on chromosome 3q21.3 that encodes transmembrane protein adipocyte-associated 1 expressed in most tissues, especially in heart, placenta and kidney, and plays role in lipid metabolism and in ageing. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity.
Protein name
Transmembrane protein adipocyte-associated 1
Other name
TPRA1; GPR175; PP6566; Transmembrane protein adipocyte-associated 1; Integral membrane protein GPR175
Human protein sequence Database
Q86W33
Mouse protein sequence database
Q99MU1
Rat protein sequence database
Q791F6
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
Ubiquitous, with higher levels in heart, placenta and kidney.
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