Immunogen
The antiserum was produced against synthesized peptide derived from human GPR42. AA range:12-61
Specificity
GPR42 Polyclonal Antibody detects endogenous levels of GPR42 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
GPR42, also named as GPR42P, FFAR1L and GPR41L, belongs to the G-protein coupled receptor 1 family. GPR42 appears to have arisen by tandem duplication of FFAR3 and have lost the ability to activate G-protein family in respose to carboxylate ligands primarily due to an amino acid change at position 174. It is an orphan receptor.
Protein name
G-protein coupled receptor 42
Other name
GPR42; GPR42P; G-protein coupled receptor 42
Human protein sequence Database
O15529
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .