Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR92. AA range:241-290
Specificity
GPR92 Polyclonal Antibody detects endogenous levels of GPR92 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
lysophosphatidic acid receptor 5(LPAR5) Homo sapiens This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008],
Function
function:Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.,
Protein name
Lysophosphatidic acid receptor 5
Other name
LPAR5; GPR92; GPR93; Lysophosphatidic acid receptor 5; LPA receptor 5; LPA-5; G-protein coupled receptor 92; G-protein coupled receptor 93
Fields
>>Rap1 signaling pathway;>>Phospholipase D signaling pathway;>>PI3K-Akt signaling pathway;>>Regulation of actin cytoskeleton;>>Pathogenic Escherichia coli infection;>>Pathways in cancer
Human protein sequence Database
Q9H1C0
Mouse protein sequence database
Q149R9
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.
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