Molecular weight (DA)
120kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human LAMP1. AA range:211-260
Specificity
CD107a Polyclonal Antibody detects endogenous levels of CD107a protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],
Function
function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,
Protein name
Lysosome-associated membrane glycoprotein 1
Other name
LAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a
Fields
>>Autophagy - animal;>>Lysosome;>>Phagosome;>>Tuberculosis
Human protein sequence Database
P11279
Mouse protein sequence database
P11438
Rat protein sequence database
P14562
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Cytolytic granule membrane ; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). .
Tissue expression
Brain,Liver,Pancreas,Placenta,Plasma,Testis,
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