Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human IL20RB. AA range:141-190
Specificity
IL-20Rβ Polyclonal Antibody detects endogenous levels of IL-20Rβ protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009],
Function
function:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.,similarity:Belongs to the type II cytokine receptor family.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer with IL20RA and heterodimer with IL22RA1.,tissue specificity:Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.,
Protein name
Interleukin-20 receptor subunit beta
Other name
IL20RB; DIRS1; Interleukin-20 receptor subunit beta; IL-20 receptor subunit beta; IL-20R-beta; IL-20RB; IL-20R2
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>JAK-STAT signaling pathway
Human protein sequence Database
Q6UXL0
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
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