Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human OR4K3. AA range:266-315
Specificity
Olfactory receptor 4K3 Polyclonal Antibody detects endogenous levels of Olfactory receptor 4K3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
Function
function:Odorant receptor .,polymorphism:A single nucleotide deletion at position Met-205 in the gene coding for this protein is reponsible for functional diversity thus producing a pseudogene.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
Olfactory receptor 4K3
Abbreviation
Olfactory receptor 4K3
Other name
OR4K3; OR4K3P; Olfactory receptor 4K3; Olfactory receptor OR14-14
Fields
>>Olfactory transduction
Human protein sequence Database
Q96R72
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
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