Molecular weight (DA)
93kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TAS1R3. AA range:326-375
Specificity
T1R3 Polyclonal Antibody detects endogenous levels of T1R3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015],
Function
function:Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.,online information:The taste experience -Issue 55 of February 2005,similarity:Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.,subunit:Forms homodimers or heterodimers with TAS1R1 and TAS1R2.,
Protein name
Taste receptor type 1 member 3
Other name
TAS1R3; T1R3; TR3; Taste receptor type 1 member 3; Sweet taste receptor T1R3
Fields
>>Taste transduction;>>Carbohydrate digestion and absorption
Human protein sequence Database
Q7RTX0
Mouse protein sequence database
Q925D8
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
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