Molecular weight (DA)
27kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NET-5. AA range:72-121
Specificity
NET-5 Polyclonal Antibody detects endogenous levels of NET-5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009],
Function
PTM:Glycosylated.,similarity:Belongs to the tetraspanin (TM4SF) family.,subcellular location:Colocalizes with GP6 in tetraspanin microdomains on the platelet surface.,subunit:Found in a complex with GP6.,tissue specificity:Expressed in megakaryocytes and platelets (at protein level).,
Protein name
Tetraspanin-9
Other name
TSPAN9; NET5; Tetraspanin-9; Tspan-9; Tetraspan NET-5
Human protein sequence Database
O75954
Mouse protein sequence database
Q8BJU2
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein . Colocalizes with GP6 in tetraspanin microdomains on the platelet surface. .
Tissue expression
Expressed in megakaryocytes and platelets (at protein level).
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