Immunogen
The antiserum was produced against synthesized peptide derived from human NPTN. AA range:106-155
Specificity
Neuroplastin Polyclonal Antibody detects endogenous levels of Neuroplastin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009],
Function
PTM:N-glycosylated.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Isoform 1 is ubiquitous.,
Protein name
Neuroplastin
Abbreviation
Neuroplastin
Other name
NPTN; SDFR1; SDR1; Neuroplastin; Stromal cell-derived receptor 1; SDR-1
Human protein sequence Database
Q9Y639
Mouse protein sequence database
P97300
Rat protein sequence database
P97546
Cellular localization
Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cell junction, synapse, postsynaptic density .
Tissue expression
Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).
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