Molecular weight (DA)
31kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD200. AA range:171-220
Specificity
CD200 Polyclonal Antibody detects endogenous levels of CD200 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
Function
function:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD200R1.,
Protein name
OX-2 membrane glycoprotein
Other name
CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD200
Human protein sequence Database
P41217
Mouse protein sequence database
O54901
Rat protein sequence database
P04218
Cellular localization
Cell membrane; Single-pass type I membrane protein.
Tissue expression
Blood,Brain,Fetal brain,
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