Molecular weight (DA)
15kD
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human IFITM1. AA range:1-50
Specificity
CD225 Polyclonal Antibody detects endogenous levels of CD225 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.,induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
Function
function:Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.,induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
Protein name
Interferon-induced transmembrane protein 1
Other name
IFITM1; CD225; IFI17; Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225
Fields
>>B cell receptor signaling pathway
Human protein sequence Database
P13164
Mouse protein sequence database
Q9D103
Rat protein sequence database
Cellular localization
Cell membrane ; Single-pass membrane protein . Lysosome membrane .
Tissue expression
Bone (at protein level). Levels greatly elevated in colon cancer, cervical cancer, esophageal cancer and ovarian cancer. Expressed in glioma cell lines.
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