Molecular weight (DA)
73kD
Immunogen
The antiserum was produced against synthesized peptide derived from human DUSP16. AA range:571-620
Specificity
MKP-7 Polyclonal Antibody detects endogenous levels of MKP-7 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
dual specificity phosphatase 16(DUSP16) Homo sapiens This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010],
Function
catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Involved in the inactivation of MAP kinases.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
Protein name
Dual specificity protein phosphatase 16
Other name
DUSP16; KIAA1700; MKP7; Dual specificity protein phosphatase 16; Mitogen-activated protein kinase phosphatase 7; MAP kinase phosphatase 7; MKP-7
Fields
>>MAPK signaling pathway
Human protein sequence Database
Q9BY84
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
Tissue expression
Bone marrow,Brain,Duodenum,PCR rescued clones,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车