Molecular weight (DA)
88kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TB10B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
TBC1 domain family member 10B(TBC1D10B) Homo sapiens Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010],
Function
function:May act as a GTPase-activating protein.,similarity:Contains 1 Rab-GAP TBC domain.,
Gene Name
TBC1D10B FP2461
Protein name
TBC1 domain family member 10B (Rab27A-GAP-beta)
Human protein sequence Database
Q4KMP7
Mouse protein sequence database
Q8BHL3
Rat protein sequence database
Cellular localization
Cytoplasm . In melanocytes, located at the periphery of cells.
Tissue expression
Brain,Epithelium,Ovary,Placenta,PNS,Teratocarcinoma,Testis,Uterus,
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