Immunogen
Synthesized peptide derived from human CD2
Specificity
The antibody can specifically recognize human CD2 protein.
Source
Monoclonal Mouse IgG2b, Kappa
Formulation
PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
Dilution rate
IHC-p 1:200-400, WB 1:200-1000,
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],
Function
function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,
Protein name
CD 2;CD2;CD2 antigen (p50), sheep red blood cell receptor;CD2 antigen;CD2 molecule;CD2_HUMAN;Erythrocyte receptor;FLJ46032;LFA-2;LFA-3 receptor;LFA2;LFA3 receptor;Ly-37;Lymphocyte function antigen 2;l
Other name
CD 2;CD2;CD2 antigen (p50), sheep red blood cell receptor;CD2 antigen;CD2 molecule;CD2_HUMAN;Erythrocyte receptor;FLJ46032;LFA-2;LFA-3 receptor;LFA2;LFA3 receptor;Ly-37;Lymphocyte function antigen 2;lymphocyte-function antigen-2;OTTHUMP00000024366;Rosette receptor;Sheep erythrocyte receptor;SRBC;T cell surface antigen CD2;T-cell surface antigen CD2;T-cell surface antigen T11/Leu-5;T-lymphocyte surface CD2 antigen;T11
Fields
>>Cell adhesion molecules;>>Hematopoietic cell lineage
Human protein sequence Database
P06729
Mouse protein sequence database
P08920
Rat protein sequence database
P08921
Cellular localization
Membranous
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