Immunogen
Synthesized peptide derived from human Cytokeratin 15 (CK15)
Specificity
This antibody detects endogenous levels of Cytokeratin 15 (CK15) at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:100. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
Function
miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,tissue specificity:Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.,
Protein name
Cytokeratin 15 (CK15)
Abbreviation
Cytokeratin 15
Other name
Keratin, type I cytoskeletal 15 (Cytokeratin-15;CK-15;Keratin-15;K15)
Fields
>>Estrogen signaling pathway;>>Staphylococcus aureus infection
Human protein sequence Database
P19012
Mouse protein sequence database
Rat protein sequence database
Cellular localization
nucleus,intermediate filament,extracellular exosome,
Tissue expression
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.
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