Immunogen
Synthesized peptide derived from human CD23
Specificity
This antibody detects endogenous levels of CD23 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:100. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
Function
function:This receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).,miscellaneous:There are two kinds of Fc receptors for IgE, which differ in both structure and function: high affinity receptors on basophils and mast cells and low affinity receptors on lymphocytes and monocytes.,online information:CD23,PTM:N- and O-glycosylated.,similarity:Contains 1 C-type lectin domain.,subcellular location:Also exists as a soluble excreted form.,
Gene Name
FCER2 CD23A CLEC4J FCE2 IGEBF
Other name
Low affinity immunoglobulin epsilon Fc receptor (BLAST-2;C-type lectin domain family 4 member J;Fc-epsilon-RII;Immunoglobulin E-binding factor;Lymphocyte IgE receptor;CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form]
Fields
>>Hematopoietic cell lineage;>>Epstein-Barr virus infection
Human protein sequence Database
P06734
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Also exists as a soluble excreted form, sCD23.
Tissue expression
B-cell,Blood,
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