Immunogen
Synthesized peptide derived from human OR4Q2 AA range: 94-144
Specificity
This antibody detects endogenous levels of OR4Q2 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
Function
function:Odorant receptor .,polymorphism:A single nucleotide insertion at position Cys-180 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Fields
>>Olfactory transduction
Human protein sequence Database
P0C623
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.