Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human HOXB9. AA range:201-250
Specificity
Hox-B9 Polyclonal Antibody detects endogenous levels of Hox-B9 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008],
Function
developmental stage:Expressed in whole embryos and fetuses at 5-9 weeks from conception.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Abd-B homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein Hox-B9
Other name
HOXB9; HOX2E; Homeobox protein Hox-B9; Homeobox protein Hox-2.5; Homeobox protein Hox-2E
Human protein sequence Database
P17482
Mouse protein sequence database
P20615
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Muscle,Placenta,
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