Molecular weight (DA)
47kD
Immunogen
The antiserum was produced against synthesized peptide derived from human IRX1. AA range:221-270
Specificity
IRX1 Polyclonal Antibody detects endogenous levels of IRX1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011],
Function
similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Iroquois-class homeodomain protein IRX-1
Other name
IRX1; IRXA1; Iroquois-class homeodomain protein IRX-1; Homeodomain protein IRXA1; Iroquois homeobox protein 1
Human protein sequence Database
P78414
Mouse protein sequence database
P81068
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Brain,Lung,
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