Molecular weight (DA)
33kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MEOX2. AA range:151-200
Specificity
MOX-2 Polyclonal Antibody detects endogenous levels of MOX-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008],
Function
function:Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.,polymorphism:The poly-His region of MEOX2 is polymorphic and the number of His varies in the population.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with RNF10.,tissue specificity:Embryo and placenta.,
Protein name
Homeobox protein MOX-2
Other name
MEOX2; GAX; MOX2; Homeobox protein MOX-2; Growth arrest-specific homeobox; Mesenchyme homeobox 2
Human protein sequence Database
P50222
Mouse protein sequence database
P32443
Rat protein sequence database
P39020
Cellular localization
Nucleus . Nucleus speckle .
Tissue expression
Embryo,Heart,Skin,
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