Immunogen
Synthesized peptide derived from Six2 . at AA range: 30-110
Specificity
Six2 Polyclonal Antibody detects endogenous levels of Six2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. [provided by RefSeq, Dec 2008],
Function
function:May be involved in limb tendon and ligament development.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Strongly expressed in skeletal muscle.,
Protein name
Homeobox protein SIX2
Other name
SIX2; Homeobox protein SIX2; Sine oculis homeobox homolog 2
Human protein sequence Database
Q9NPC8
Mouse protein sequence database
Q62232
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Strongly expressed in skeletal muscle. Expressed in Wilms' tumor and in the cap mesenchyme of fetal kidney (at protein level).
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